Sebastian Mirkin Selected Research

Conjugated (USP) Estrogens (Premarin)

1/2019	Endometrial safety of low-dose vaginal estrogens in menopausal women: a systematic evidence review.
11/2016	Pooled Analysis of the Effects of Conjugated Estrogens/Bazedoxifene on Vasomotor Symptoms in the Selective Estrogens, Menopause, and Response to Therapy Trials.
10/2016	Effect of conjugated estrogens/bazedoxifene on postmenopausal bone loss: pooled analysis of two randomized trials.
5/2016	Gynecologic Safety of Conjugated Estrogens Plus Bazedoxifene: Pooled Analysis of Five Phase 3 Trials.
4/2016	The effect of conjugated estrogens/bazedoxifene therapy on body weight of postmenopausal women: pooled analysis of five randomized, placebo-controlled trials.
1/2016	Conjugated estrogens and bazedoxifene in minority populations: pooled analysis of four phase 3 trials.
3/2015	Recent advances help understand and improve the safety of menopausal therapies.
11/2014	Development of conjugated estrogens/bazedoxifene, the first tissue selective estrogen complex (TSEC) for management of menopausal hot flashes and postmenopausal bone loss.
8/2014	Differential effects of menopausal therapies on the endometrium.
7/2014	Menopause-specific quality of life across varying menopausal populations with conjugated estrogens/bazedoxifene.

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Sebastian Mirkin Research Topics

Disease

20	Atrophy 11/2020 - 03/2010
12	Osteoporosis 05/2016 - 01/2012
10	Breast Neoplasms (Breast Cancer) 01/2019 - 08/2005
9	Dyspareunia 11/2020 - 03/2015
7	Hemorrhage 01/2020 - 12/2003
7	Postmenopausal Osteoporosis 10/2016 - 11/2013
6	Endometrial Hyperplasia 01/2020 - 09/2014
4	Uterine Hemorrhage (Uterine Bleeding) 05/2016 - 10/2004
3	Metrorrhagia (Spotting) 01/2020 - 07/2014
3	Neoplasms (Cancer) 01/2019 - 09/2014
3	Hyperplasia 01/2019 - 08/2014
3	Mastodynia 05/2016 - 03/2014
2	Endometrial Neoplasms (Endometrial Cancer) 01/2019 - 05/2016
2	Hot Flashes 11/2016 - 11/2014
2	Premenstrual Dysphoric Disorder 05/2012 - 01/2012
1	Amenorrhea 01/2020
1	Sleepiness 12/2018
1	Pruritus (Itching) 05/2017
1	Ovarian Cysts (Ovarian Cyst) 05/2016
1	Body Weight (Weight, Body) 04/2016
1	Stroke (Strokes) 08/2015
1	Venous Thromboembolism 08/2015
1	Bone Fractures (Bone Fracture) 08/2015
1	Coronary Disease (Coronary Heart Disease) 03/2015
1	Dementia (Dementias) 03/2015
1	Osteoporotic Fractures 11/2014
1	Bone Resorption 11/2013
1	Premenstrual Syndrome (Premenstrual Tension) 05/2012

Drug/Important Bio-Agent (IBA)

18	Estrogens (Estrogen)FDA Link 01/2019 - 03/2010
15	bazedoxifeneIBA 11/2016 - 03/2010
13	Conjugated (USP) Estrogens (Premarin)FDA Link 01/2019 - 03/2010
10	Estradiol (Delestrogen)FDA LinkGeneric 11/2020 - 08/2005
10	Progestins (Progestagens)IBA 01/2019 - 01/2004
9	Selective Estrogen Receptor Modulators (SERM)IBA 01/2016 - 11/2013
8	Capsules (Microcapsules)IBA 01/2020 - 01/2017
8	TX-004HRIBA 09/2017 - 12/2016
7	Hormones (Hormone)IBA 07/2014 - 12/2003
4	Progesterone FDA LinkGeneric 01/2020 - 08/2005
4	Levonorgestrel (Plan B)FDA LinkGeneric 05/2012 - 08/2005
3	TX-001HRIBA 01/2020 - 12/2018
3	Ethinyl Estradiol (Estinyl)FDA LinkGeneric 05/2012 - 12/2010
2	Medroxyprogesterone Acetate (Depo-Provera)FDA LinkGeneric 05/2016 - 08/2005
2	Raloxifene Hydrochloride (Evista)FDA Link 01/2016 - 09/2014
2	Estrogen ReceptorsIBA 09/2014 - 08/2005
2	Oral ContraceptivesIBA 05/2012 - 12/2010
2	Messenger RNA (mRNA)IBA 08/2005 - 07/2004
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2005 - 01/2004
1	LubricantsIBA 01/2019
1	MineralsIBA 08/2015
1	OspemifeneIBA 03/2015
1	Paroxetine (Paxil)FDA LinkGeneric 03/2015
1	Diphosphonates (Bisphosphonates)IBA 11/2014
1	Denosumab FDA Link 11/2014
1	strontium ranelate (protelos)IBA 11/2014
1	Tamoxifen FDA LinkGeneric 09/2014
1	OsteocalcinIBA 11/2013
1	collagen type I trimeric cross-linked peptideIBA 11/2013
1	CytokinesIBA 08/2007
1	SteroidsIBA 08/2007
1	Norethindrone (Norethisterone)FDA LinkGeneric 08/2005
1	Protein Isoforms (Isoforms)IBA 08/2005
1	tiboloneIBA 08/2005
1	Progesterone Receptors (Progesterone Receptor)IBA 08/2005
1	Progesterone CongenersIBA 08/2005
1	Mifepristone (RU 486)FDA Link 10/2004
1	Contraceptive Agents (Contraceptives)IBA 07/2004
1	Thrombospondin 1IBA 07/2004

Therapy/Procedure

17	Therapeutics 01/2019 - 12/2003
1	Hysterectomy 08/2015
1	Contraception (Birth Control) 07/2004